RDNAT Co. was founded in 1974 by Isaiah Jennings, a graduate from Yale with a degree in biology and biogenetics. When he wanted to cure his son, Thomas of his Lactose Intolerance, he started is own company and built it up from the ground. Ever since that day, RDNAT has been growing and becoming a larger, smarter, and better company. RDNAT is the best company for genetic engineering. Using the latest state-of-the-art technology RDNAT can precisely change the genes of a certain organism for whatever reason you may need.Humulin-r.jpeg "R DNA is great DNA !"

Recombinant DNA was first discovered by Peter Lobban and A. Dale Kaiser at the Stanford University Department of Biochemistry. Later Lobban and Kaiser published a book including the 1972 paper and a 1973 paper. These papers include techniques to isolate of amplify genes or DNA and insert them into other cells. Recombinant DNA was made possible by finding, isolation and application of restriction endolnucleases by Werner Arber, Daniel Nathans and Hamilton Smith and received the Nobel Prize in medicine, in 1978. A breakthrough in recombinant was in 1977 by Herbert Boyer he produced the human insulin. This is now a medicine called Humulin which is approved by the FDA and is commercially available.

Science of Recombinant DNA Technology
Recombinant DNA Technology current usage is to isolate one gene or any other segment of DNA, enabling scientist to determine its nucleotide sequence, study its transcripts ,mutate it in highly specific ways , and reinsert the modified sequence into a living organism. Recombinant DNA or rDNA is a form of artificial DNA that is created by combing two or more genes that would not normally be together by gene splicing. Recombinant DNA alters the traits for certain reason. Recombinant DNA can rid of lactose intolerance or hemophilia or even cancers. Recombinant is related to cloning. The use of rDNA provides the first cell from which the organism is then supposed to repeat when it goes through cell division. When there is bacteria remaining it’s an example due to the use of viral vectors in medicine that contain rDNA and are put into a plasmid. Plasmids are a self-replicating form of DNA that is in a lot of bacteria like E.Coli. This technology combines DNA from the genes of different organisms. RDNAT hopes to perfect this technology and make it possible for anyone to access.
This shows how a gene is inserted into a plasmid.

This picture shows insulin being inserted into a human cell.

How we use Recombinant DNA Technology090514-02-glowing-monkey_big.jpeg at RDNAT.
Recombinant DNA has many uses that can help people and has many benefits. Recombinant DNA can transfer genes from one organism to another. Recombinant DNA can help test for mutated proteins that can be associated with breast cancer, retinoblastoma and neurofibromatosis. It can also can diagnose if people carry hereditary diseases like cystic fibrosis, the Huntington’s disease, tay-sachs, or Duchene muscular dystrophy gene. It can help people suffering from cystic fibrosis, rheumatoid arthritis, vascular disease, and certain types of cancers. These people may now benefit from progress made in gene therapy. Gene therapy is replacing a mutated gene that causes disease with a brand new copy of that gene. Adding the new gene can help the body fight the disease.
Since recombinant DNA can replace genes for new ones, you can even add the gene of glowing to anything. There is a company called Glofish that uses a glowing gene and inserts it into the DNA of a fish and then it makes the fish glow. Many scientist have made many animals glow like monkeys, rabbits and mice.
Recombinant DNA also is used to kill insects. Round Up is a pesticide, that has genectically engineered bacteria to protect the plants.

Our future plans for RDNAT
RDNAT's first idea is to help people who are lactose intolerant. We want to help people who are lactose intolerant because of the founders son who has suffered is whole life trying to find foods he could eat. We hope to cure lactose intolerance by perfecting the process of replacing the gene with a new one.
We also would want to prevent birth defects like Tay-Sachs disease, if we were able to figure out if that gene is in the baby before it is born we could possibly change the gene and replace it with a new one before the baby is born.
Another plan RDNAT has is to create what someone would think is there perfect child. We would want to creat a process of choosing certain genes that have traits that could make you baby short, tall or even how smart they are! By taking the DNA of two humans and combining it to make the perfect child. RDNAT hopes to achieve all of these plans in the near future.

Fhs-bio-wiki / FrontPage. Web. 23 Dec. 2010. http://fhs-bio-wiki.pbworks.com/.

"Glowing Baby Monkeys." Crazy Party Fun-time Media Newz (In HD). Web. 23 Dec. 2010. http://cpftmn.blogspot.com/2009/06/glowing-baby-monkeys.html.

"Recombinant DNA." Wikipedia, the Free Encyclopedia. Web. 23 Dec. 2010. http://en.wikipedia.org/wiki/Recombinant_DNA.

"Recombinant DNA Technology." Home. Web. 23 Dec. 2010. <http://www.follistim.com/Consumer/FollistimAQCartridge/RecombinantDNAtechnology/index.asp>.

"What Is Gene Therapy? - Genetics Home Reference." Genetics Home Reference - Your Guide to Understanding Genetic Conditions. Web. 23 Dec. 2010. http://ghr.nlm.nih.gov/handbook/therapy/genetherapy.

"Why Should You Buy Humulin Regular at DrugsPRO?" DrugsPro - Best Online Drugstore. Brand and Generic Drugs Are Available for Lowest Prices on Our Pharmacy Online! Web. 23 Dec. 2010. http://www.drugspro.org/diabetes/humulin-regular.html.
Copyrighted by: Lauren Fecura, Ben Fisher, Elsa Hemerding and Gabe Greagan