Recombinant+DNA+Technology+9-10

**__RDT Corporation__**

//__Who Are We? __ // CEO Dr. Quinn Hernandez founded RDT Corp. in 2003 upon graduating Dartmouth University with a master’s degree in Biogenetics. As a young girl she was fascinated by the anatomy of living things and had a glowing fish as a pet, a product of recombinant DNA technology. When she was a sophomore at Quiskatuna High School, she was inspired by her biology teacher, Mr. Mitch Sennings. He helped her discover her passion for biology and more specifically recombinant DNA technology. From then on she decided to be involved in the study of recombinant DNA technology. After graduating college with a masters degree in biogenetics she founded a small company that she had been planning during college, this small company became one of the largest recombinant DNA technology companies in the U.S.

 //﻿__What Do We Do?__ // __﻿__Since it was founded in 2003, what we at the RDT Corp. do is we combine the DNA from the genes of two organisms to create a new organism. This organism has new and exciting traits that are not present and can’t come about in Mother Nature itself. CEO Quinn Hernandez says “Over the years we have crossed many genes of animals for example; giving the gene for glowing from a jellyfish and giving it to a common pet fish and it now glows as well. This fish is now known as the glow fish.” The RDT corp. has high tech. labs and operation centers all over the United States including Alaska and Hawaii all working hard on researching and learning to achieve our biggest goal yet. Hernandez says “our biggest goal right now is to discover how to splice (or combine) genes from an extinct animal like the wooly mammoth and cross it with a close relative like the elephant. We could possibly create a wooly mammoth/elephant cross bread to bring the wooly mammoth back from extinction.” If you are interested in our field of work and you would like to help us achieve our goal, call us at our headquarters which is located in Baltimore, Maryland and you must have a degree in genetics to become a member. Remember, Quinn Hernandez’s slogan is for the corporation is “Here at the RDT Corp. it’s in our genes to create new organisms for the future.” ﻿ **__Contact Us-__**

//__History of Recombinant DNA Technology__// Peter Lobban, a graduate student, and A. Dale Kaiser were the first to propose the technique of recombinant DNA technology. They realized the technique with many others including; Jackson, Symons, and Berg; and Stanley Norman Cohen, Chang, Herbert Boyer, and Helling in the years of 1972 to 1974. They published their findings in papers which they described techniques to confine and strengthen DNA segments or genes and implant them into another cell which created a transgenic bacterium. Werner Arber, Daniel Nathans, and Hamilton Smith discovered that confinement and application of restriction endonucleases, which made it possible to use recombinant DNA technology. They all won the 1978 Nobel Peace Prize in Medicine for their discovery. Then biosynthetic “human” insulin was produced by Herbert Boyer in 1977, it was a major development for recombinant DNA technology. The first brand name approved by the FDA that was made via recombinant DNA technology was Humulin.
 * Phone: 518-555-9255**
 * E-mail: quinnhernandezsec@rdtcorp.org.**

//__Science Behind Our Company’s Technology __// In our company, we have studied and researched many things about Recombinant DNA Technology. To understand and to be able to use this type of technology, there are things in a cell that must be known. Restriction enzymes are proteins that DNA at specific base pairs, a vector is the carrier of the genetic material, sticky ends are the DNA fragment ends, and DNA ligase are enzymes that are used to join the sticky ends together. There are many advantages to abuse the power to clone and insert new and improved cells that could make things to do in everyday life a little simpler. We do not just insert new cells into humans, we are also able to insert new cells that could help things such as weed control, insect resistance, and oil clean-ups. Producing new cells such as these could increase the efficiency of doing everyday house work. Also by using this technology, we are able to produce genetically modified food that will last longer than its normal expiration date. Using this type of cell cloning is also useful for humans. By taking a cell and cloning it, you could easy identify mutations in the body and make it easier to be tested. Also with one simple cell, you could be able to tell if a human is a carrier of such diseases as cystic fibrosis gene, the Huntington’s disease gene, the Tay-Sachs disease gene, or the Duchene muscular dystrophy gene. With this type of technology, we would be able to take a cell out that could have a lactose deficiency, and then we would be able to add the lactase enzyme to the cell lacked, and then clone the new and improved cell to then put back into the body. They are able to make vaccines using Recombinant DNA technology to treat diseases such as hepatitis B. Also one of the first uses was making insulin for humans with type 2 diabetes. Using recombinant DNA technology has advanced our society it many ways. //__Current Uses of Technology__// - Impacts diagnosis and the treatments of a disease and genetic disorders - Transfer of genes from one organism to another (Transgenic animals, such as glofish pictured to the left and a glowing monkey picture at the bottom of the website) - Many things have been advanced due to recombinant DNA technology such as protein structure/function, regulation research and gene expression - Recombinant DNA technology is linked to modern medicine - Agricultural uses such as genetically engineered bacteria’s sprayed on crops to protect them, other plants have been able to sustain insects because of recombinant DNA (For example the company Roundup which logo is pictured to the left.) //__The Future of RDT Corporation __// <span style="color: #000000; font-family: 'Calibri','sans-serif'; font-size: 11pt; text-indent: 0.5in;">Have you ever imagined owning a dream pet? Here at RDT, that is just what we hope to accomplish in the near future. We are working on taking the uses of recombinant DNA technology to a new and more exciting level. CEO Dr. Quinn Hernandez has recently talked with fellow scientists here at RDT and they have expressed much interest in creating your “dream pet”. For example, by crossing the genes of a cat with the genes of a dog, we can create a hybrid with the look and size of a cat, but it can be just as smart and affectionate as a dog. To do this, we will take a dog’s genes that make it intelligent and take out the cat’s intelligence gene. Then, we replace the cat’s intelligence gene with the dog’s intelligence gene, and now since the hybrid has the gene, it will be passed down through the offspring and that hybrid will have the intelligence (including the obedience) of a dog, but it will still appear to look like a cat. <span style="color: #000000; font-family: 'Calibri','sans-serif'; font-size: 11pt; text-indent: 0.5in;">Another exiting dream that we hope to turn into reality is to begin to take genes from two humans, and splicing them giving the offspring of the two humans the best traits possible. For example, we can take a human’s gene that makes them tall, and cross it with another human’s athletic gene, and the offspring turns out to be both tall and athletic. There are many possibilities with this method and the choice could be yours of what you want your offspring to be like. <span style="font-family: 'Calibri','sans-serif'; font-size: 11pt;">The last future use that we are currently researching is if we could possibly find a person who is immune to a certain illness like for example AIDS, we could splice their DNA with the DNA of people without this gene, and it could be spread through the offspring of all of these people and eventually most people would have this immunity. This could be an amazing breakthrough in the world.

__<span style="font-family: 'Cambria','serif'; font-size: 16pt;">References: __ -<span style="font-family: 'Calibri','sans-serif'; font-size: 11pt; line-height: 115%;">Cooper, Geoffry. “Recombinant DNA.” __Answers.com.__ Answers Corporation, 21 December 2010. Web.21 Dec 2010. [] - “Recombinant DNA technology.” Schering-__plough.__ Schering Corporation, 2009. Web. 21 Dec 2010. [] - P., Justin. "Glowing Baby Monkeys." Blogspot, 1st June 2009. Web. 23 Dec 2010. []. - Raheem, Abdul. "Recombiant DNA technology and molecular cloning." //Indyarocks//. 9 September 2010. Web. 23 Dec 2010. []. - Smith, Sharron. "Reombinant DNA." //Chemistry Explained//. Advameg Inc., n.d. Web. 23 Dec 2010. []. - <span style="color: #333333; font-family: Calibri; font-size: 9pt; letter-spacing: 1.5pt; line-height: 115%;">"Recombinant DNA Technology." //Fierce Biotech//. Fierce Markets, n.d. Web. 23 Dec 2010. []. <span style="color: #333333; font-family: Calibri; font-size: 9pt; letter-spacing: 1.5pt; line-height: 115%;"> - "Recombinant DNA Technology." //Fierce Biotech//. Fierce Markets, n.d. Web. 23 Dec 2010. [].

** Copyright; Katelyn Lampman, Jacob McKenna, Christine Minniti, Greg Manzoni, Quai Quai Simmons **